Non-Invasive Ventilation Versus High-flow Nasal Oxygen in Intensive Care Units

NARecruitingINTERVENTIONAL
Enrollment

670

Participants

Timeline

Start Date

February 2, 2023

Primary Completion Date

March 1, 2026

Study Completion Date

August 1, 2026

Conditions
Post Extubation Respiratory Failure
Interventions
PROCEDURE

High-Flow Oxygen

Humidified and heated oxygen with a gas flow at least 50 L/min through nasal cannula

PROCEDURE

Non invasive ventilation

NIV will be carried out in pressure-support mode with a minimal pressure-support level of 5 cmH2O targeting a tidal volume around 6 to 8 mL/kg of predicted bodyweight, a positive end-expiratory pressure (PEEP) level at least 8 cm H2O, and FiO2 adjusted to obtain adequate oxygenation

Trial Locations (1)

Unknown

RECRUITING

CHU Poitiers, Poitiers

All Listed Sponsors
lead

Poitiers University Hospital

OTHER