NCT05686798View on ClinicalTrials.gov

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

PHASE1RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

November 29, 2022

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2026

Conditions
Malignant Glioma of BrainAstrocytomaMalignant AstrocytomaBrain TumorGliomaBrain CancerGlioblastomaGlioblastoma MultiformeGBM
Interventions
BIOLOGICAL

Ad5-yCD/mutTKSR39rep-ADP adenovirus and fractionated stereotactic radiosurgery (fSRS)

Ad5-yCD/mutTKSR39rep-ADP adenovirus will be injected intratumoral

Trial Locations (1)

48202

RECRUITING

Henry Ford Health System, Detroit

All Listed Sponsors
lead

Henry Ford Health System

OTHER