Study of NM8074 in Patients with AHUS with Evidence of Ongoing Thrombotic Microangiopathy

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

February 28, 2027

Conditions
AHUS - Atypical Hemolytic Uremic Syndrome
Interventions
DRUG

NM8074

NM8074 will be administered as an intravenous infusion. In Cohort 1, all subjects will be administered 20 mg/kg of NM8074 intravenously every two weeks for a total of 7 doses from Day 1 to Day 85 of the Treatment Period. Patients in Cohort 2 will receive weekly doses of 10 mg/kg for a total of 4 doses from Day 1 to Day 22 followed by biweekly doses at 20 mg/kg for a total of 5 doses from Day 29 to Day 85.

Sponsors
All Listed Sponsors
lead

NovelMed Therapeutics

INDUSTRY

NCT05684159 - Study of NM8074 in Patients with AHUS with Evidence of Ongoing Thrombotic Microangiopathy | Biotech Hunter | Biotech Hunter