Monoclonal Antibodies
Total Trials
9
As Lead Sponsor
As Collaborator
0
Total Enrollment
130
NCT05642546
First-in-Human (FIH) Clinical Study of NM8074 in Healthy Adult Volunteers
Phase: Phase 1
Role: Lead Sponsor
Start: Aug 12, 2020
Completion: Jun 15, 2022
NCT05684159
Study of NM8074 in Patients with AHUS with Evidence of Ongoing Thrombotic Microangiopathy
Phase: Phase 2
Start: Jul 31, 2025
Completion: Feb 28, 2027
NCT05647811
Study of NM8074 in Adult C3 Glomerulopathy Patients
Phase: Phase 1/2
Start: Nov 30, 2025
Completion: Jul 31, 2027
NCT06454110
Study of NM8074 in Patients With Immunoglobulin A Nephropathy (IgAN)
NCT05646563
Study of NM8074 in Adult PNH Patients with Inadequate Response to Soliris
Start: Jan 31, 2026
Completion: Jan 31, 2028
NCT05646524
Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy
Start: Apr 30, 2026
Completion: Sep 30, 2028
NCT05731050
Study of NM8074 in Soliris-Treated Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Start: Jun 30, 2026
Completion: Mar 31, 2028
NCT06226662
Study of NM8074 in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)
NCT06887738
Study of NM8074 in Patients with Dermatomyositis (DM)
Completion: Dec 31, 2028
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