Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Gait Characteristics in Parkinson's Disease

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 1, 2022

Primary Completion Date

February 15, 2023

Study Completion Date

February 15, 2023

Conditions
Parkinson DiseaseGait Disorders, Neurologic
Interventions
DEVICE

Noninvasive transcutaneous auricular vagus nerve stimulation at 100Hz

Noninvasive electrostimulation will be applied to the left cyma conchae through the Nemos® electrode with the following parameters: square-shaped pseudobiphasic pulse, interpulse duration 80μs, pulse width 300μs, pulse intensity 0,1mA above the perceptual threshold at 100Hz. The intensity for each separate stimulation will be adjusted for each participant at the beginning of the experiment.

DEVICE

Noninvasive transcutaneous auricular vagus nerve stimulation at 25Hz

Noninvasive electrostimulation will be applied to the left cyma conchae through the Nemos® electrode with the following parameters: square-shaped pseudobiphasic pulse, interpulse duration 80μs, pulse width 300μs, pulse intensity 0,1mA above the perceptual threshold at 25Hz. The intensity for each separate stimulation will be adjusted for each participant at the beginning of the experiment.

DEVICE

Noninvasive transcutaneous earlobe stimulation at 25Hz

Noninvasive electrostimulation will be applied to the left earlobe through the Nemos® electrode with the following parameters: square-shaped pseudobiphasic pulse, interpulse duration 80μs, pulse width 300μs, pulse intensity 0,1mA above the perceptual threshold at 25Hz. The intensity for each separate stimulation will be adjusted for each participant at the beginning of the experiment.

Trial Locations (1)

1000

Neurology Department, UMC Ljubljana, Ljubljana

All Listed Sponsors
lead

University Medical Centre Ljubljana

OTHER