NCT05681754View on ClinicalTrials.gov

Endo-perio Disease - Treatment Outcomes Using Conventional and Hydraulic Calcium Silicate Sealer With or Without LPRF

NANot yet recruitingINTERVENTIONAL
Enrollment

115

Participants

Timeline

Start Date

May 31, 2023

Primary Completion Date

May 31, 2027

Study Completion Date

May 31, 2033

Conditions
Endodontic DiseasePeriodontitis
Interventions
PROCEDURE

Experimental: RCT using hydraulic calcium silicate sealer and L-PRF + GTR

Endodontic treatment with hydraulic calcium silicate sealer, followed by periodontal surgery using GTR +/- LPRF

PROCEDURE

Experimental: RCT using conventional sealer and L-PRF + GTR

Endodontic treatment with conventional sealer followed by periodontal treatment with PRF + GTR

PROCEDURE

Experimental: RCT using hydraulic calcium silicate sealer and GTR

Endodontic treatment with hydraulic calcium silicate sealer, followed by periodontal surgery using GTR only

PROCEDURE

Active Comparator: RCT using conventional sealer and GTR (bone substitute + collagen membrane)

Endodontic treatment with conventional sealer followed by periodontal treatment with GTR only

Trial Locations (1)

Unknown

Guy'S and St Thomas' Nhs Foundation Trust, London

All Listed Sponsors
lead

King's College London

OTHER

NCT05681754 - Endo-perio Disease - Treatment Outcomes Using Conventional and Hydraulic Calcium Silicate Sealer With or Without LPRF | Biotech Hunter | Biotech Hunter