NCT05681312View on ClinicalTrials.gov

Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars

PHASE3RecruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

May 8, 2024

Primary Completion Date

September 1, 2024

Study Completion Date

September 9, 2024

Conditions
Post Operative Pain
Interventions
DRUG

systemic proteolytic enzyme (Tibrolin)

Tibrolin is a fixed dose combination of(Trypsin 48 mg, Bromelain 90 mg) and a bioflavonoid (Rutoside 100 mg)

DRUG

Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg

Amoxicillin is given with metronidazole 500mg 1\*3' Doliprane 1000mg is given 1\*1

Trial Locations (1)

10011

RECRUITING

Dunya Abdulmuniem Mahmood, Baghdad

All Listed Sponsors
lead

University of Baghdad

OTHER