NCT05678621View on ClinicalTrials.gov

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

November 30, 2022

Primary Completion Date

April 30, 2027

Study Completion Date

April 30, 2027

Conditions
Haematological MalignancyHypogammaglobulinemia
Interventions
DRUG

trimethoprim-sulfamethoxazole (co-trimoxazole)

Doxycycline is an alternative for participants with hypersensitivity to co-trimoxazole.

DRUG

amoxycillin/clavulanic acid and ciprofloxacin

clindamycin is an alternative to amoxycillin/clavulanic acid for participants with hypersensitivity to penicillin.

DRUG

Immunoglobulins

Intravenous monthly immunoglobulin or subcutaneous weekly immunoglobulin

Trial Locations (7)

2065

NOT_YET_RECRUITING

Royal North Shore, St Leonards

2139

RECRUITING

Concord Hospital, Concord

2605

NOT_YET_RECRUITING

Canberra Hospital, Garran

3004

RECRUITING

The Alfred Hospital, Melbourne

3021

RECRUITING

Sunshine Hospital, St Albans

3084

RECRUITING

Austin Hospital, Heidelberg

3168

RECRUITING

Monash Medical Centre, Clayton

All Listed Sponsors
lead

Monash University

OTHER