Role of Paclitaxel in Stricture Urethra

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

June 1, 2022

Primary Completion Date

June 1, 2025

Study Completion Date

October 1, 2025

Conditions
Stricture Urethra
Interventions
PROCEDURE

DVIU with paclitaxel injection

Cystourethroscopy will be performed using a 22 Fr rigid cystoscope to allow for ureteric catheter 3F/a wire to be passed through the stricture and into the urinary bladder. DVIU will be performed by cold-knife incisions at the 12-, 3-, and 9 o'clock positions through the full thickness of the fibrosis to healthier appearing tissue. A 23 Fr Wolf (Vernon Hills, IL) injection scope and a standard injection needle was used to inject 30 mg/5mL of paclitaxel vial, 1.5 mL will be injected along the length of each incision into healthier appearing tissue for a total of 5 mL.

PROCEDURE

DVIU

DVIU

Trial Locations (1)

Unknown

RECRUITING

Mohamed Fawzy Salman, Cairo

All Listed Sponsors
lead

Al-Azhar University

OTHER