The (Cost-)Effectiveness of Surgical Excision of Colorectal Endometriosis Compared to ART Treatment Trajectory

RecruitingOBSERVATIONAL
Enrollment

339

Participants

Timeline

Start Date

February 17, 2023

Primary Completion Date

July 31, 2028

Study Completion Date

January 1, 2029

Conditions
Endometriosis, RectumEndometriosis of ColonSubfertility, Female
Interventions
PROCEDURE

Laparoscopic excision of endometriosis, including colorectal endometriosis

Laparoscopic resection of deep endometriosis, including colorectal endometriosis, in a (candidate) level 2 centre of expertise. Complete resection can exist of either 'shaving' of the nodule from the bowel (leaving the lumen closed), discoid excision or segmental resection, depending on the nodule size and extent of disease.

PROCEDURE

In vitro fertilisation or intracytoplasmic sperm injection

IVF/ICSI treatment trajectory (maximum of 3 cycles), according to the local protocol. Preferably preceded by 3 months downregulation with either Gonadotrophin-releasing hormone (GnRH) analogue or oral contraceptive pill. One IVF/ICSI cycle is defined as the transfer of all the embryos created after one follicle puncture until pregnancy confirmation or failure of the last embryo transfer.

Trial Locations (10)

Unknown

RECRUITING

Catharina Ziekenhuis, Eindhoven

RECRUITING

Medical Spectrum Twente, Enschede

RECRUITING

University Medical Center Groningen, Groningen

RECRUITING

Leiden University Medical Center, Leiden

RECRUITING

Maastricht University Medical Center, Maastricht

RECRUITING

Radboud university medical center, Nijmegen

RECRUITING

Erasmus Medical Centre, Rotterdam

RECRUITING

Haaglanden Medical Center, The Hague

RECRUITING

Utrecht Medical Center, Utrecht

RECRUITING

Nederlandse Endometriose Kliniek (Reinier de Graaf Gasthuis), Voorburg

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Haaglanden Medical Centre

OTHER

collaborator

University Medical Center Groningen

OTHER

collaborator

Maastricht University Medical Center

OTHER

collaborator

Radboud University Medical Center

OTHER

collaborator

Reinier de Graaf Groep

OTHER

collaborator

Catharina Ziekenhuis Eindhoven

OTHER

collaborator

UMC Utrecht

OTHER

lead

Leiden University Medical Center

OTHER

NCT05677269 - The (Cost-)Effectiveness of Surgical Excision of Colorectal Endometriosis Compared to ART Treatment Trajectory | Biotech Hunter | Biotech Hunter