NCT05676463View on ClinicalTrials.gov

MRI Guided Radiation Therapy for the Treatment of High Risk Prostate Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

November 16, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2027

Conditions
Prostate AdenocarcinomaStage IIIB Prostate Cancer AJCC v8Stage IIIC Prostate Cancer AJCC v8
Interventions
PROCEDURE

MRI-guided Intensity-Modulated Radiation Therapy

Undergo MRI-guided IMRT

DRUG

Antiandrogen Therapy

Receive SOC ADT

PROCEDURE

PSMA PET Scan

Undergo PSMA PET scan

PROCEDURE

Computed Tomography

Undergo CT

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

Bone Scan

Undergo bone scan

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

OTHER

Quality-of-Life Assessment

Ancillary studies

Trial Locations (1)

19107

Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia

All Listed Sponsors
lead

Thomas Jefferson University

OTHER