NCT05675345View on ClinicalTrials.gov

Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 28, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Acute Hypoxemic Respiratory Failure
Interventions
DEVICE

HFNC only

HFNC for 45 minutes, with FiO2 titrated to SpO2 of 90-97%

DEVICE

HFNC + CNEP10

HFNC with CNEP of 10 cmH2O for 45 minutes, with FiO2 titrated to SpO2 of 90-97%

DEVICE

HFNC + CNEP20

HFNC with CNEP of 20 cmH2O for 45 minutes, with FiO2 titrated to SpO2 of 90-97%

DEVICE

HFNC + CNEP30

HFNC with CNEP of 30 cmH2O for 45 minutes, with FiO2 titrated to SpO2 of 90-97%

Trial Locations (1)

10032

RECRUITING

Columbia University Irving Medical Center, New York

All Listed Sponsors
lead

Columbia University

OTHER