50
Participants
Start Date
June 28, 2023
Primary Completion Date
July 31, 2026
Study Completion Date
October 31, 2026
Bayesian based dose adjustment of enoxaparin
"A first recommended dose of enoxaparin 50 IU/kg subcutaneously is administered during transplantation or within the first 24 hours.~Then a Bayesian estimate of individual pharmacokinetics is performed to adapt the next twice daily (Hour 12;Hour 24) enoxaparin dose until achievement of the target on two consecutive measurements. Then anti-Xa activity will be evaluated once a day until day 7."
Usual dose adjustment of enoxaparin
A first recommended dose of enoxaparin 50 IU/kg is administered during transplantation or within the first 24 hours. Then anti-Xa activity is measured and twice-daily (hour 12 ; hour 24) enoxaparin empirical dose-adjustment is performed according to the usual practices in the investigating centers to target.
RECRUITING
Hôpital Pellegrin, Bordeaux
NOT_YET_RECRUITING
Hôpital Pellegrin, Bordeaux
NOT_YET_RECRUITING
Hôpital Necker Enfants Malades, Paris
RECRUITING
Hôpital Necker - Enfants malades, Paris
RECRUITING
Hôpital Robert Debré, Paris
NOT_YET_RECRUITING
Hôpital Robert Debré, Paris
RECRUITING
CHU Félix Guyon, La Réunion
NOT_YET_RECRUITING
CHU Félix Guyon, La Réunion
RECRUITING
Hôpital Mère Enfant, Lyon
NOT_YET_RECRUITING
Hôpital Mère Enfant, Lyon
RECRUITING
Hôpital de la Villeneuve, Montpellier
NOT_YET_RECRUITING
Hôpital de la Villeneuve, Montpellier
RECRUITING
Hôtel Dieu, Nantes
NOT_YET_RECRUITING
Hôtel Dieu, Nantes
RECRUITING
Hôpital de Hautepierre, Strasbourg
NOT_YET_RECRUITING
Hôpital de Hautepierre, Strasbourg
NOT_YET_RECRUITING
Hôpital des Enfants, Toulouse
NOT_YET_RECRUITING
Hôpital des Enfants, Toulouse
Assistance Publique - Hôpitaux de Paris
OTHER