A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia

PHASE2RecruitingINTERVENTIONAL
Enrollment

249

Participants

Timeline

Start Date

December 9, 2022

Primary Completion Date

July 16, 2027

Study Completion Date

August 14, 2034

Conditions
Anemia
Interventions
BIOLOGICAL

Luspatercept

Specified dose on specified days

DRUG

Placebo

Specified dose on specified days

Trial Locations (36)

807

RECRUITING

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City

10002

RECRUITING

National Taiwan University Hospital, Nan Gang Qu

10043

ACTIVE_NOT_RECRUITING

Local Institution - 0020, Orbassano

10700

RECRUITING

Siriraj Hospital, Bangkok

11411

NOT_YET_RECRUITING

Local Institution - 0034, Riyadh

11527

ACTIVE_NOT_RECRUITING

Local Institution - 0009, Goudi

16128

ACTIVE_NOT_RECRUITING

Local Institution - 0026, Genova

31982

NOT_YET_RECRUITING

Local Institution - 0035, Al-Ahsa

34093

NOT_YET_RECRUITING

Local Institution - 0021, Topkapı

40447

RECRUITING

China Medical University Hospital, Taichung

50586

NOT_YET_RECRUITING

Local Institution - 0032, Kuala Lumpur

65000

NOT_YET_RECRUITING

Local Institution - 0031, Mueang Phitsanulok

80100

RECRUITING

Hospital Sultanah Aminah, Johor Bahru

80131

ACTIVE_NOT_RECRUITING

Local Institution - 0028, Napoli

80138

RECRUITING

"Universita degli Studi della Campania Luigi Vanvitelli - AOU - Clinica Pediatrica", Napoli

229899

NOT_YET_RECRUITING

Local Institution - 0036, Singapore

510120

RECRUITING

Sun Yat-sen Memorial Hospital, Sun Yat-Sen University, Guangzhou

510515

RECRUITING

Nanfang Hospital of Southern Medical University, Guangzhou

518025

RECRUITING

Shenzhen Second People's Hospital, Shenzhen Shi

525000

RECRUITING

Maoming People's Hospital, Maoming Shi

528000

RECRUITING

The First People's Hospital of Foshan, Foshan

530021

RECRUITING

People's Liberation Army The 923rd Hospital, Nanning

RECRUITING

The First Affiliated Hospital of Guangxi Medical University, Nanning

545006

RECRUITING

Liuzhou People's Hospital, Liuzhou

570203

ACTIVE_NOT_RECRUITING

Local Institution - 0011, Haikou

570311

RECRUITING

Hainan General Hospital, Haikou

650032

COMPLETED

Local Institution - 0012, Kunming

B3K 6R8

WITHDRAWN

Local Institution - 0008, Halifax

546 42

WITHDRAWN

Local Institution - 0005, Thessaloniki

412 21

ACTIVE_NOT_RECRUITING

Local Institution - 0007, Larissa

265 04

ACTIVE_NOT_RECRUITING

Local Institution - 0018, Rio

115 27

ACTIVE_NOT_RECRUITING

Local Institution - 0006, Athens

Unknown

COMPLETED

Local Institution - 0025, Hong Kong

WITHDRAWN

Local Institution - 0024, Hong Kong Island

09121

WITHDRAWN

Local Institution - 0022, Cagliari

06230

NOT_YET_RECRUITING

Local Institution - 0027, Altındağ

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY