Magnesium Sulphate Versus Ketamine as an Adjuvant to Bupivacaine in Pectoral Nerve Block During Mastectomy

PHASE2CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

December 1, 2022

Primary Completion Date

December 1, 2023

Study Completion Date

May 1, 2024

Conditions
CancerBreast
Interventions
DRUG

Use of Bupivacaine in pectoral nerve block in mastectomy

Pectoral nerve block will be performed and patients will be given 30 mL of 0.25% bupivacaine hydrochloride and It will be divided into 10 mL injected between the 2 pectoral muscles on the interfascial plane, and 20 mL will be injected between the pectoralis minor and the serratus anterior muscles

DRUG

use of Ketamine as adjuvants to bupivacaine in pectoral nerve block in mastectomy

Pectoral nerve block will be performed and Patients will be given 30 mL of 0.25% bupivacaine hydrochloride plus ketamine hydrochloride (1 mg/kg) and It will be divided into 10 mL injected between the 2 pectoral muscles on the interfascial plane, and 20 mL will be injected between the pectoralis minor and the serratus anterior muscles

DRUG

Use of Magnesium Sulfate as adjuvants to bupivacaine in pectoral nerve block in mastectomy

Pectoral nerve block will be performed and Patients will be given 30 mL 0.25% Bupivacaine hydrochloride plus Magnesium Sulfate ( 28 ml Bupivacaine 0.25% plus 2ml magnesium sulfate 50%) and It will be divided into 10 mL injected between the 2 pectoral muscles on the interfascial plane, and 20 mL will be injected between the pectoralis minor and the serratus anterior muscles

Trial Locations (1)

62511

faculty of medicine ,Beni-Suef university, Banī Suwayf

All Listed Sponsors
lead

Beni-Suef University

OTHER