PBI for Breast in Situ Carcinoma of Intermediate Low Risk As Local Adjuvant Treatment

NAActive, not recruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

January 9, 2023

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2029

Conditions
Breast Cancer
Interventions
RADIATION

external beams radiotherapy

"External beam radiation therapy uses high doses of radiation to destroy cancer cells and shrink tumors. A large machine aims radiation at the cancer. The allowed schedules for external beams radiotherapy are:~* 40 Gy in 15 fractions;~* 30 Gy in 5 fractions;~* 40 Gy or 38.5 in 10 twice-daily fractions (each daily dose must be separated by at least 6 hours)."

RADIATION

brachytherapy

"Brachytherapy is a form of radiation therapy where a sealed radiation source is placed inside or next to the area requiring treatment.~The schedule for brachytherapy are:~* 32 Gy in 8 twice-daily fractions for HDR;~* 30.3 Gy in 7 twice-daily fractions for HDR;~* 50Gy 0.60-0.80 Gy/hour (1 pulse/hour, 24 hours/day) for PDR."

Trial Locations (1)

20089

IRCCS Istituto Clinico Humanitas, Rozzano

Sponsors
All Listed Sponsors
collaborator

Mediolanum Cardio Research

OTHER

lead

Istituto Clinico Humanitas

OTHER

NCT05663294 - PBI for Breast in Situ Carcinoma of Intermediate Low Risk As Local Adjuvant Treatment | Biotech Hunter | Biotech Hunter