Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

NARecruitingINTERVENTIONAL
Enrollment

144

Participants

Timeline

Start Date

January 24, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

August 31, 2027

Conditions
DementiaMemory LossAlzheimer DiseaseExecutive DysfunctionMobility Limitation
Interventions
DEVICE

Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active)

Transcranial electrical stimulation (tES), via alternating and direct current, will be administered to the participant in their home by their caregiver administrator to the left angular gyrus and prefrontal cortex.

DEVICE

Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (sham)

A sham transcranial electrical stimulation (tES) will be administered to the participant in their home by their caregiver administrator to the left angular gyrus and prefrontal cortex. It will physically mimic active stimulation.

DEVICE

Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (sham)

Transcranial electrical stimulation (tES), via alternating and direct current, will be administered to the participant in their home by their caregiver administrator. Active tACS to the left angular gyrus and sham tDCS to the prefrontal cortex.

DEVICE

Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (active)

Transcranial electrical stimulation (tES), via alternating and direct current, will be administered to the participant in their home by their caregiver administrator. Sham tACS to the left angular gyrus and active tDCS to the prefrontal cortex.

Trial Locations (1)

02131

RECRUITING

Hinda and Arthur Marcus Institute for Aging Research, Boston

All Listed Sponsors
collaborator

BrightFocus Foundation

OTHER

collaborator

National Institute on Aging (NIA)

NIH

lead

Hebrew SeniorLife

OTHER