Physiology Optimized Versus Angio-guided PCI

NACompletedINTERVENTIONAL
Enrollment

305

Participants

Timeline

Start Date

December 1, 2022

Primary Completion Date

June 20, 2023

Study Completion Date

December 7, 2024

Conditions
Coronary Artery DiseasePercutaneous Coronary Intervention
Interventions
OTHER

Microcatheter-derived FFR

FFR pullback trace is obtained through the manual retrieval performed after the positioning of the microcatheter FFR in the distal portion of the vessel. The pullback speed should be steady and the overall duration would be between 20 and 40 seconds. Then, the Interventional Cardiologist has to decide the procedural plan according to the pullback trace aiming to obtain an optimal post-PCI result in terms of physiology. FFR with pullback can be repeated after stenting to check and correct the result if needed.

OTHER

Angiography-derived FFR

FFR pullback trace is automatically obtained after the 3-Dimensional reconstruction of the vessel through angiography derived FFR. Then, Interventional Cardiologist has to decide the procedural plan according to the pullback result aiming to obtain an optimal post-PCI result in terms of physiology. Angiography-derived FFR can be repeated after stenting to check and correct the result if needed.

OTHER

Angiography-guided PCI

Interventional Cardiologist will perform PCI plan according to his/her the evaluation of angiography.

Trial Locations (2)

44124

University Hospital of Ferrara, Cona

Unknown

Santa Maria Goretti Hospital, Latina

All Listed Sponsors
lead

University Hospital of Ferrara

OTHER