NCT05658731View on ClinicalTrials.gov

Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

NARecruitingINTERVENTIONAL
Enrollment

338

Participants

Timeline

Start Date

May 17, 2023

Primary Completion Date

December 31, 2032

Study Completion Date

December 31, 2035

Conditions
Brain TumorHead and Neck Cancer
Interventions
RADIATION

substructure informed planning

Radiation Therapy with substructure informed planning determined by the PI.

OTHER

Neurocognitive Testing

California Verbal Learning Test (CVLT) and other cognition assessments.

DIAGNOSTIC_TEST

MRI

Magnetic resonance imaging (MRI) using whole brain diffusion tensor imaging (DTI) and resting state functional MRI (rsfMRI).

Trial Locations (2)

20016

RECRUITING

Sibley Memorial Hospital, Washington D.C.

21287

RECRUITING

Johns Hopkins Hospital, Baltimore

All Listed Sponsors
collaborator

United States Department of Defense

FED

collaborator

Clark Charitable Foundation

UNKNOWN

lead

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER