A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

PHASE2RecruitingINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

December 9, 2022

Primary Completion Date

December 9, 2025

Study Completion Date

December 9, 2025

Conditions
Non Small Cell Lung CancerNon Small Cell Lung Cancer MetastaticNon-small Cell CarcinomaNSCLCNSCLC Stage IV
Interventions
RADIATION

L-SABR

L-SABR will be delivered in a week during which the patient receives no chemotherapy. L-SABR can be on the same week or even day as anti-PD-(L)1 therapy.

BIOLOGICAL

Anti-PD-(L)1 based immunotherapy

Standard of care treatment (anti-PD-(L)1 based immunotherapy +/- platinum based chemotherapy

DRUG

Platinum based chemotherapy

Standard of care treatment (anti-PD-(L)1 based immunotherapy +/- platinum based chemotherapy

Trial Locations (9)

10065

RECRUITING

Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York

10604

RECRUITING

Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison

11553

RECRUITING

Memorial Sloan Kettering Nassau (All protocol activities), Rockville Centre

11725

RECRUITING

Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities), Commack

18103

RECRUITING

Lehigh Valley Health Network (Data Collection Only), Allentown

33143

RECRUITING

BAPTIST ALLIANCE - MCI (Data Collection Only), Miami

07920

RECRUITING

Memorial Sloan Kettering at Basking Ridge (All Protocol Activities), Basking Ridge

07748

RECRUITING

Memorial Sloan Kettering Monmouth (All Protocol Activities), Middletown

07645

RECRUITING

Memorial Sloan Kettering Bergen (All protocol activities), Montvale

All Listed Sponsors
lead

Memorial Sloan Kettering Cancer Center

OTHER