The Role of the Tumor Molecular Profile (CMS), UGT1A1 Genotype and Beta-glucuronidase Activity of the Intestinal Microbiota for Treatment Efficiency, Toxicity, Survival and Quality of Life in Patients With Metastatic or Unresectable Colorectal Cancer During Irinotecan-based Systemic Treatment

RecruitingOBSERVATIONAL
Enrollment

104

Participants

Timeline

Start Date

January 9, 2023

Primary Completion Date

October 31, 2025

Study Completion Date

December 31, 2028

Conditions
Colorectal Neoplasms
Trial Locations (1)

6229 HX

RECRUITING

Maastricht UMC+, Maastricht

All Listed Sponsors
collaborator

Maastricht University

OTHER

collaborator

Wageningen University & Research

UNKNOWN

collaborator

Fontys Hogeschool

UNKNOWN

collaborator

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Catharina Ziekenhuis

UNKNOWN

collaborator

University of North Carolina (USA)

UNKNOWN

collaborator

Oncology patientenpanel MUMC

UNKNOWN

collaborator

Stichting Kanker.nl

UNKNOWN

collaborator

Van Weel-Bethesda Ziekenhuis

UNKNOWN

collaborator

VieCuri Medisch Centrum voor Noord-Limburg

UNKNOWN

collaborator

Gelderse Vallei Hospital

OTHER

collaborator

Danone Nutricia Research

INDUSTRY

collaborator

Clinical Trial Center Maastricht B.V.

OTHER

collaborator

Dutch Colorectal Cancer Group (DCCG)

UNKNOWN

collaborator

Prospectief Landelijk CRC Cohort (PLCRC)

UNKNOWN

collaborator

CRC-guideline committee

UNKNOWN

collaborator

CZ zorgverzekeraar

UNKNOWN

collaborator

Landelijke Werkgroep Diëtisten Oncologie (LWDO)

UNKNOWN

collaborator

Rode Kruis Ziekenhuis Beverwijk

UNKNOWN

lead

Maastricht University Medical Center

OTHER