300
Participants
Start Date
February 8, 2022
Primary Completion Date
December 31, 2028
Study Completion Date
December 31, 2028
Comparison of chemotherapy vs. chemoradiotherapy
"Chemotherapy (paclitaxel-carboplatin) vs. chemoradiotherapy (paclitaxel-carboplatin followed by whole pelvic radiotherapy)~Patients assigned to chemotherapy receive paclitaxel (175 mg/m2) and carboplatin (area under curve, 5) every 3 weeks for 6 cycles. The pelvic radiotherapy dose is 45 to 50.4 Gy over 5 to 6 weeks (1.8 Gy per day for 25 to 28 fractions)."
Comparison of VBT vs. WPRT
"Vaginal brachytherapy vs. whole pelvic radiotherapy~Patients randomized to vaginal brachytherapy receive cuff brachytherapy at 21 Gy in 3 fractions of 7 Gy at 0.5 cm depth. The pelvic radiotherapy dose is 45 to 50.4 Gy over 5 to 6 weeks (1.8 Gy per day for 25 to 28 fractions)."
RECRUITING
Helsinki University Hospital, Helsinki
Turku University Hospital
OTHER_GOV
Tampere University Hospital
OTHER
Kuopio University Hospital
OTHER
Oulu University Hospital
OTHER
Kymenlaakso Central Hospital Kotka Finland
OTHER
Päijänne Tavastia Central Hospital
OTHER
South Carelia Central Hospital
OTHER
University of Helsinki
OTHER