Experimental and Clinical Investigation of the Implant Surface Roughness Reduction Effect on Early-stage Fibrosis

NACompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

January 20, 2021

Primary Completion Date

January 1, 2024

Study Completion Date

February 13, 2024

Conditions
Capsular Contracture Associated With ImplantForeign-Body ReactionWounds and InjuriesTissue Expander Disorder
Interventions
OTHER

Patient Satisfaction Questionnaire

During regular clinical examinations patient will go through a short questionnaire at week 4, 16 and 24 to check patient satisfaction with expanders

DIAGNOSTIC_TEST

Pregnancy test

Pre-op; to sufficiently check pregnancy as exclusion criteria

PROCEDURE

Blood draw

pre- expander implantation, alongside anaesthesia pre- expander explantation and exchange with definite implant alongside anaesthesia - no additional vein irritation needed

PROCEDURE

Expander based breast reconstruction

implantation of 2 different expanders intraindividually

PROCEDURE

Ultrasound of breast

Measurement of capsular thickness pre- expander removal

OTHER

S(AE )monitoring

(S)AE evaluation will be performed from Visit 1 (Day 0 = Expander implantation) to Visit 15 (Day 168-196 = Reoperation) according to visit plan.

Trial Locations (1)

6020

Medical University of Innsbruck, Department for Plastic, Aethetic and Reconstructive Surgery, Innsbruck

All Listed Sponsors
lead

Medical University Innsbruck

OTHER

NCT05648929 - Experimental and Clinical Investigation of the Implant Surface Roughness Reduction Effect on Early-stage Fibrosis | Biotech Hunter | Biotech Hunter