Personalized Hemodynamic Management in High-risk Major Abdominal Surgery

NARecruitingINTERVENTIONAL
Enrollment

1,128

Participants

Timeline

Start Date

October 8, 2023

Primary Completion Date

October 31, 2025

Study Completion Date

December 31, 2025

Conditions
Cardiac OutputSurgeryPostoperative ComplicationsAnesthesia
Interventions
OTHER

Personalized hemodynamic management

Personalized hemodynamic management: Intraoperative cardiac index will be maintained at least at the preoperative baseline cardiac index. Preoperative baseline cardiac index will be determined one day before surgery with the patient being awake and resting in the supine position using the Starling Fluid Management System (Baxter, Deerfield, IL, USA) Preoperative baseline cardiac index will be determined with the patient being awake and resting in supine position using the Starling Fluid Management System (Baxter, Deerfield, IL, USA) (usually at least one day before surgery). We will define the individual preoperative baseline cardiac index as the average value over a 5 min period at rest (minimum cardiac index threshold: 2.2 L min-1 m-2). Intraoperative cardiac index will be measured using the Baxter Starling Fluid Management System.

Trial Locations (12)

Unknown

RECRUITING

Medical University of Graz, Graz

NOT_YET_RECRUITING

University Hospital Plzen, Pilsen

RECRUITING

Hvidovre Hospital, Copenhagen

RECRUITING

Rigshospitalet, Copenhagen

RECRUITING

University Medical Center Copenhagen Bispebjerg and Frederiksberg, Copenhagen

NOT_YET_RECRUITING

University Hospital RWTH Aachen, Aachen

RECRUITING

University Hospital Düsseldorf, Düsseldorf

RECRUITING

University Medical Center Hamburg, Hamburg

RECRUITING

University Medical Center Schleswig Holstein, Lübeck, Lübeck

RECRUITING

University Hospital Marburg, Marburg

RECRUITING

LMU Munich, Munich

RECRUITING

Clínica Universidad de Navarra, Pamplona

All Listed Sponsors
lead

Universitätsklinikum Hamburg-Eppendorf

OTHER