Effects of Berberine in Reducing Abdominal Visceral Adipose Tissue Among Individuals with Obesity and NAFLD

PHASE4CompletedINTERVENTIONAL
Enrollment

337

Participants

Timeline

Start Date

July 6, 2023

Primary Completion Date

August 9, 2024

Study Completion Date

August 9, 2024

Conditions
ObesityObesity, AbdominalNAFLD
Interventions
DRUG

Berberine plus lifestyle intervention

"berberine hydrochloride 500mg twice a day for 6 months plus lifestyle intervention.~Lifestyle intervention is based on Guidelines of prevention and treatment for non-alcoholic fatty liver disease (2018 update) and China Blue Paper on Obesity Prevention and Control, including health education on diet, physical activity and weight loss, etc."

BEHAVIORAL

Placebo plus lifestyle intervention

"Placebo with identical shape, colour, odour and taste twice a day plus lifestyle intervention.~Lifestyle intervention is based on Guidelines of prevention and treatment for non-alcoholic fatty liver disease (2018 update) and China Blue Paper on Obesity Prevention and Control, including health education on diet, physical activity and weight loss, etc."

Trial Locations (1)

Unknown

Fuwai Hospital, Chinese Academy of Medical Sciences, National Center for Cardiovascular Diseases, Beijing

All Listed Sponsors
lead

China National Center for Cardiovascular Diseases

OTHER_GOV