Dietary Approach to Mild-to-moderate Psoriasis

NARecruitingINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

July 30, 2024

Study Completion Date

October 31, 2025

Conditions
PsoriasisGluten Sensitivity
Interventions
OTHER

Open wheat challenge

Patients randomized to intervention diet group will have to follow a diet with elimination of wheat and cow's milk products for 2 months; after that they will be exposed to an open wheat challenge, with reintroduction of wheat. After 2 weeks of open diet, or whenever dermatologic, intestinal and/or extraintestinal symptoms should return or intensify, all patients will be revaluated and will end the study.

OTHER

Placebo challenge

Patients randomized to control diet group will have to follow a diet with elimination of rice and turkey's meat products for 2 months; after that they will crossover to a wheat and cow's milk products free diet and, finally, after 2 months, they will be exposed to an open wheat challenge, with reintroduction of wheat. After 2 weeks of open diet, or whenever dermatologic, intestinal and/or extraintestinal symptoms should return or intensify, all patients will be revaluated and will end the study.

Trial Locations (3)

90127

RECRUITING

Dermatology Department of the University Hospital 'P. Giaccone' of Palermo, Italy,, Palermo

RECRUITING

Internal Medicine Department of the University Hospital of Palermo, Palermo

90146

RECRUITING

"Internal Medicine Division of the Cervello-Villa Sofia Hospital", Palermo

All Listed Sponsors
collaborator

Aurelio Seidita

UNKNOWN

lead

University of Palermo

OTHER

NCT05644782 - Dietary Approach to Mild-to-moderate Psoriasis | Biotech Hunter | Biotech Hunter