NCT05644301View on ClinicalTrials.gov

INflammation-based Stratification for Immune-Targeted Augmentation in Major Depressive Disorder

PHASE3RecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

September 21, 2023

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Major Depressive DisorderInflammation
Interventions
DRUG

Celecoxib

Oral capsule, 200 mg, twice daily, for 12 weeks

DRUG

Minocyclin

Oral capsule, 100 mg, twice daily, for 12 weeks

DRUG

Placebo

Oral capsule, no active substance, twice daily, for 12 weeks

Trial Locations (3)

2570

RECRUITING

UPC Duffel, Duffel

Unknown

RECRUITING

UZ Brussel, Brussels

RECRUITING

Katholiek Universiteit Leuven Campus Kortenberg, Leuven

All Listed Sponsors
collaborator

Research Foundation Flanders

OTHER

collaborator

KU Leuven

OTHER

collaborator

Vrije Universiteit Brussel

OTHER

collaborator

Amsterdam UMC, location VUmc

OTHER

lead

Universiteit Antwerpen

OTHER