Technical R&D and Demonstration of Intelligent Medical Care in Alzheimer's Disease's Management

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 3, 2022

Primary Completion Date

December 9, 2025

Study Completion Date

December 9, 2025

Conditions
Alzheimer DiseaseSubjective Cognitive DeclineMild Cognitive ImpairmentMild Dementia
Interventions
DEVICE

Transcutaneous electrical acupoint stimulation&Music therapy

"Procedure: electro-acupuncture;Points: Shenting(DU24), Benshen(BG13), Tou Wei (ST8).The specially-made pad is stick on pierced acupoints, until local sour and heavy feeling coming. The electric stimulator is applied to bilateral BG13 and ST8, with dilatational wave,10/50 Hz and electric current 1-5mA(milliampere).Every session lasts for 30 min per day. The participants are treated continuously for 8 weeks for 3 sessions a week, 24 sessions for each participants in all.~Selecting the participants' music of memory and music of favourite(Music is purchased and downloaded from music stores), forming a personalized music playlist, and the decibel level is suitable for participants.~The treatment is designed based on recent literature research in 10 years, former result and expert consensus.~Other Names:~* JS-502-A Intelligent and portable electroacupuncture~* apparatus(Han's low frequency neuromodulator, made in China)"

DRUG

Donepezil hydrochloride tablets or carpalatine bitartrate tablets

"① Donepezil hydrochloride tablets 5 mg, once a day, one tablet each time, before going to bed. The treatment period is 6 months.~② Carpalatine heavy tartrate tablets 1.5mg, 1 tablet/time 2 weeks before treatment, twice a day, breakfast and dinner with food, swallow. If there is no obvious adverse reaction after 2 weeks, the dosage can be increased to 2 tablets/time, twice a day. The treatment period is 6 months."

Trial Locations (2)

710003

RECRUITING

Shaanxi Hospital of Traditional Chinese Medicine,, Xi'an

NOT_YET_RECRUITING

Shaanxi Hospital of Traditional Chinese Medicine, Xi'an

All Listed Sponsors
lead

Shaanxi Hospital of Traditional Chinese Medicine

OTHER