NCT05635786View on ClinicalTrials.gov

Early Recanalization After Intravenous Thrombolysis With Tenecteplase Versus Alteplase in Distal Vessel Occlusion Strokes

CompletedOBSERVATIONAL
Enrollment

319

Participants

Timeline

Start Date

January 2, 2023

Primary Completion Date

November 21, 2024

Study Completion Date

November 21, 2024

Conditions
Acute Distal Vessel Occlusion Stroke
Interventions
DRUG

Alteplase (0.9mg/kg)

Intravenous thrombolysis with Alteplase (0.9 mg/kg, maximum 90 mg) with 10% of the dose given as a bolus followed by an infusion lasting 60 minutes.

DRUG

Tenecteplase (0.25mg/kg)

Intravenous thrombolysis with Tenecteplase (0.25mg/kg, maximum 25 mg) with 100% of the dose given as a bolus.

Trial Locations (1)

91106

Centre Hospitalier Sud Francilien, Corbeil-Essonnes

All Listed Sponsors
lead

Centre Hospitalier Sud Francilien

OTHER