Enhancing the A in SAFE for Trachoma

PHASE4CompletedINTERVENTIONAL
Enrollment

34,630

Participants

Timeline

Start Date

May 4, 2022

Primary Completion Date

August 5, 2023

Study Completion Date

August 5, 2023

Conditions
Trachoma
Interventions
DRUG

Azithromycin for Routine Community-wide MDA

"Oral azithromycin, also known as the brand name Zithromax®, is a macrolide antibiotic and is used in the treatment of active trachoma. The recommended dosage for the treatment of trachoma is a single dose of 20mg/kg of body weight and is implemented by a Age-height based dosing strategy for the trachoma MDA campaigns. Oral azithromycin can be administrated in either tablet form or powder for oral suspension (POS). Zithromax® is donated by Pfizer Inc through the International Trachoma Initiative (ITI) to the South Sudan Federal Ministry of Health to use in community-wide MDA throughout South Sudan."

DRUG

Two Additional Rounds of Azithromycin for Children

An additional round of treatment will be given one week after the routine community-wide MDA, and a second additional round will be given two weeks later (3 weeks after the routine community-wide MDA).

DRUG

Azithromycin for Second Community-wide MDA

A second community-wide MDA will be given 6 to 8 months after the routine community-wide MDA. The timing of the second MDA will depend on local conditions and logistical concerns.

Trial Locations (1)

Unknown

Ministry of Health Republic of South Sudan, Juba

All Listed Sponsors
lead

Emory University

OTHER