Influence of Nutritional Status on Oncologic and Operative Outcome in Patients Operated for Retroperitoneal Sarcoma

CompletedOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

December 2, 2022

Primary Completion Date

April 4, 2024

Study Completion Date

April 4, 2024

Conditions
Retroperitoneal SarcomaBody CompositionMalnutritionSarcopeniaSarcopenic ObesityMyosteatosis
Interventions
OTHER

Measurement of body composition with computed tomography (CT)

The cross section of the third lumbar vertebrae in the CT scan images of the patients will be analyzed for assessment of body composition parameters including skeletal muscle area (SMA), muscle radiation attenuation (MRA), visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT)

DIAGNOSTIC_TEST

GLIM malnutrition criteria

GLIM criteria (Global Leadership Initiative on Malnutrition) will be applied to assess malnutrition

DIAGNOSTIC_TEST

EWGSOP2 sarcopenia criteria

EWGSOP2 criteria (Writing Group for the European Working Group on Sarcopenia in Older People 2) will be followed to determine the diagnosis of sarcopenia

DIAGNOSTIC_TEST

ESPEN-EASO criteria for sarcopenic obesity

The European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO) consensus criteria from 2018 will be applied to assess sarcopenic obesity

DIAGNOSTIC_TEST

Prognostic Nutritional Index (PNI)

Prognostic Nutritional Index is diagnostic test based on serum albumin level and total lymphocyte count

DIAGNOSTIC_TEST

The high-sensitivity modified Glasgow prognostic score

The high-sensitivity modified Glasgow prognostic score (Hs-mGPS) is an inflammation-based score consisted of C-reactive protein level and serum albumin

Trial Locations (1)

1000

Institute of Oncology Ljubljana, Ljubljana

All Listed Sponsors
lead

Institute of Oncology Ljubljana

OTHER