Combined Antidepressant and Behavioural Intervention

NACompletedINTERVENTIONAL
Enrollment

134

Participants

Timeline

Start Date

May 28, 2021

Primary Completion Date

November 17, 2023

Study Completion Date

November 17, 2023

Conditions
Low MoodDepressionAnxiety
Interventions
DRUG

Citalopram

Serotonin-reuptake inhibitor commonly used to treat depressive and anxiety disorders.

BEHAVIORAL

Behavioural Activation

A NICE recommended psychological intervention for mild to moderate depression. In behavioural activation, the person with depression and the therapist work together to identify the relationships between the activities the person undertakes and their mood. It encourages people to become less mood-dependent when planning activities and doing constructive things that they would usually avoid doing.

DRUG

Placebo

A lactose-based tablet.

Trial Locations (1)

OX3 7JX

Neurosciences Building, Warneford Hospital, Oxford

All Listed Sponsors
collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

lead

University of Oxford

OTHER