A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

579

Participants

Timeline

Start Date

March 6, 2023

Primary Completion Date

August 4, 2025

Study Completion Date

November 18, 2027

Conditions
Melanoma
Interventions
DRUG

Nivolumab + Relatlimab

Specified dose on specified days

DRUG

rHuPH20

Specified dose on specified days

Trial Locations (149)

1011

Local Institution - 0105, Lausanne

1090

Local Institution - 0037, Vienna

1200

Local Institution - 0072, Brussels

1474

Local Institution - 0158, Lørenskog

1714

Local Institution - 0156, Grålum

2065

Local Institution - 0055, Wollstonecraft

2145

Local Institution - 0033, Westmead

2298

Local Institution - 0184, Waratah

2444

Local Institution - 0172, Port Macquarie

2450

Local Institution - 0050, Coffs Harbour

2650

Local Institution - 0118, Wagga Wagga

2800

Local Institution - 0175, Orange

3004

Local Institution - 0030, Melbourne

3010

Local Institution - 0092, Bern

3084

Local Institution - 0154, Heidelberg

3100

Local Institution - 0168, Sankt Pölten

3128

Local Institution - 0059, Box Hill

3550

Local Institution - 0008, Bendigo

3844

Local Institution - 0109, Traralgon

4000

Local Institution - 0016, Liège

4575

Local Institution - 0090, Birtinya

5020

Local Institution - 0029, Salzburg

6000

Local Institution - 0078, Charleroi

6009

Local Institution - 0106, Nedlands

Local Institution - 0161, Nedlands

7000

Local Institution - 0080, Chur

8005

Local Institution - 0163, Bodø

8036

Local Institution - 0027, Graz

10117

Local Institution - 0060, Berlin

13385

Local Institution - 0117, Marseille

15006

Local Institution - 0086, A Coruña

16132

Local Institution - 0077, Genova

18045

Local Institution - 0139, Easton

18057

Local Institution - 0053, Rostock

19107

Local Institution - 0124, Philadelphia

20014

Local Institution - 0012, Donostia / San Sebastian

20133

Local Institution - 0170, Milan

20251

Local Institution - 0138, Hamburg

20520

Local Institution - 0162, Turku

21079

Local Institution - 0046, Dijon

21201

Local Institution - 0146, Baltimore

21614

Local Institution - 0038, Buxtehude

22031

Local Institution - 0115, Fairfax

23007

Local Institution - 0153, Jaén

23538

Local Institution - 0003, Lübeck

28007

Local Institution - 0040, Madrid

28009

Local Institution - 0126, Madrid

28041

Local Institution - 0004, Madrid

28050

Local Institution - 0056, Madrid

30727

Local Institution - 0021, Krakow

31059

Local Institution - 0108, Toulouse

32224

Local Institution - 0114, Jacksonville

32429

Local Institution - 0044, Minden

33000

Local Institution - 0022, Bordeaux

33521

Local Institution - 0167, Tampere

35016

Local Institution - 0045, Las Palmas de Gran Canaria

35042

Local Institution - 0089, Rennes

35043

Local Institution - 0165, Marburg

35385

Local Institution - 0065, Giessen

37044

Local Institution - 0127, Chambray-lès-Tours

37075

Local Institution - 0135, Göttingen

41009

Local Institution - 0006, Seville

44093

Local Institution - 0063, Nantes

44137

Local Institution - 0136, Dortmund

44195

Local Institution - 0169, Cleveland

45147

Local Institution - 0049, Essen

46009

Local Institution - 0041, Valencia

Local Institution - 0043, Valencia

46014

Local Institution - 0151, Valencia

53100

Local Institution - 0014, Siena

55905

Local Institution - 0071, Rochester

59000

Local Institution - 0111, Lille

60590

Local Institution - 0166, Frankfurt am Main

63003

Local Institution - 0129, Clermont-Ferrand

64100

Local Institution - 0128, Bayonne

67063

Local Institution - 0137, Ludwigshafen

68130

Local Institution - 0013, Omaha

69120

Local Institution - 0101, Heidelberg

69310

Local Institution - 0052, Pierre-Bénite

70124

Local Institution - 0051, Bari

72076

Local Institution - 0081, Tübingen

72762

Local Institution - 0189, Springdale

75475

Local Institution - 0034, Paris

76031

Local Institution - 0099, Rouen

77900

Local Institution - 0091, Olomouc

80054

Local Institution - 0007, Amiens

80113

Local Institution - 0113, Englewood

80131

Local Institution - 0084, Napoli

84107

Local Institution - 0122, Murray

85013

Local Institution - 0125, Phoenix

89081

Local Institution - 0079, Ulm

90025

Local Institution - 0098, Los Angeles

90419

Local Institution - 0112, Nuremberg

93042

Local Institution - 0011, Regensburg

94305

Local Institution - 0123, Stanford

94805

Local Institution - 0061, Villejuif

99089

Local Institution - 0039, Erfurt

1834111

Local Institution - 0026, Afula

2520598

Local Institution - 0028, Viña del Mar

4800827

Local Institution - 0143, Temuco

4941492

Local Institution - 0102, Petah-Tikvah

5262100

Local Institution - 0035, Tel Litwinsky

5507642

Local Institution - 0178, Port Montt

6423906

Local Institution - 0173, Tel Aviv

7500653

Local Institution - 0119, Santiago

7500921

Local Institution - 0017, Santiago

7510032

Local Institution - 0010, Santiago

8150513

Local Institution - 0074, Santiago

8380455

Local Institution - 0140, Recoleta

9112001

Local Institution - 0054, Jerusalem

60135237

Local Institution - 0177, Fortaleza

92868-3201

Local Institution - 0093, Orange

29043-260

Local Institution - 0180, Vitória

30130-090

Local Institution - 0107, Belo Horizonte

98700-000

Local Institution - 0025, Ijuí

90035-903

Local Institution - 0031, Porto Alegre

90610-000

Local Institution - 0058, Porto Alegre

91350-250

Local Institution - 0002, Porto Alegrelegre

89010-340

Local Institution - 0159, Blumenau

14784-400

Local Institution - 0009, Barretos

15090-000

Local Institution - 0018, São José do Rio Preto

20220-410

Local Institution - 0110, Rio de Janeiro

01321-001

Local Institution - 0130, São Paulo

T2N 5G2

Local Institution - 0141, Calgary

L8V 5C2

Local Institution - 0121, Hamilton

K1H 8L6

Local Institution - 0096, Ottawa

M4N 3M5

Local Institution - 0116, Toronto

G1J 1Z4

Local Institution - 0103, Québec

0101010

Local Institution - 0144, Santiago

128 00

Local Institution - 0083, Prague

500 05

Local Institution - 0094, Hradec Králové

708 52

Local Institution - 0082, Ostrava Poruba

182 00

Local Institution - 0095, Prague

00029

Local Institution - 0164, Helsinki

06132

Local Institution - 0032, Perugia

00168

Local Institution - 0064, Roma

0379

Local Institution - 0155, Oslo

85-796

Local Institution - 0171, Bydgoszcz

45-061

Local Institution - 0005, Opole

60-780

Local Institution - 0015, Poznan

02-781

Local Institution - 0066, Warsaw

08916

Local Institution - 0134, Badalona

08035

Local Institution - 0047, Barcelona

08036

Local Institution - 0024, Barcelona

171 64

Local Institution - 0062, Solna

222 42

Local Institution - 0097, Lund

SW3 6JJ

Local Institution - 0088, London

OX3 7LE

Local Institution - 0068, Headington, Oxford

NE7 7DN

Local Institution - 0120, Newcastle upon Tyne

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT05625399 - A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma | Biotech Hunter | Biotech Hunter