A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma

PHASE1RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 8, 2023

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2027

Conditions
Soft Tissue SarcomaBone Sarcoma
Interventions
DRUG

Cyclophosphamide

Given by IV (vein)

DRUG

attIL2-T cells

Given by IV (vein)

Trial Locations (1)

77030

RECRUITING

M D Anderson Cancer Center, Houston

All Listed Sponsors
lead

M.D. Anderson Cancer Center

OTHER