480
Participants
Start Date
December 15, 2022
Primary Completion Date
December 31, 2028
Study Completion Date
December 31, 2033
Weight loss intervention
"Subjects will receive very low-calorie diet for 8-10 weeks to introduce a rapid weight loss of approximately 10%. Once target weight is achieved, participants will be reintroduced to foods to introduce weight stability.~The male will follow the maternal randomization, i.e. weight loss if BMI ≥25 until a BMI of 23 or a weight loss of approximately 10% is obtained.~During weight loss maintenance, subjects will receive dietary counseling to follow a diet high in protein (corresponding to 22-25E%), high fiber and wholegrain while fulfilling the requirements for essential fatty acids, micronutrients and trace elements in accordance with Nordic Nutrition Recommendations (NNR) 2012.~Throughout the study period participants will be encouraged to follow the official recommendations for physical activity as recommended by the Danish health authorities 2022."
RECRUITING
University of Copenhagen, Frederiksberg
Dept. of Obstetrics and Gynecology, Hvidovre Hospital, Denmark
UNKNOWN
Department of Growth and Reproduction Rigshospitalet, Denmark
UNKNOWN
Center for Healthy Childhood, Denmark
UNKNOWN
University of Copenhagen
OTHER
Christian Mølgaard
OTHER