17
Participants
Start Date
December 1, 2023
Primary Completion Date
February 12, 2025
Study Completion Date
February 14, 2025
140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK)
The investigators propose to study the benefits nitrite therapeutics, using nitrate-rich beetroot juice to increase serum nitrite. The investigators hypothesize that increased nitrite will improve functional metrics and reduce fatigability in Veterans with long COVID as a result of enhanced skeletal muscle mitochondrial respiration. Participant will receive 140 ml per day of Beet-It nitrate beverage for 16 mmol of nitrate/day for 14 days vs the placebo.
210 ml of nitrate-depleted placebo
Participants randomized to the placebo arm will receive 210 ml of nitrate-depleted beverage (cranberry juice) per day for 14 days.
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
University of Pittsburgh
OTHER
VA Office of Research and Development
FED