Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the Thorax

PHASE2RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

March 24, 2023

Primary Completion Date

February 24, 2028

Study Completion Date

February 24, 2030

Conditions
Small Cell Lung Carcinoma
Interventions
DRUG

Durvalumab

Patients showing a disease control (defined as stable disease \[SD\], partial response \[PR\], or complete response \[CR\] according to RECIST v1.1) at the radiological evaluation performed after the end of thoracic CRT will receive durvalumab intravenously 1500 mg every 4 weeks until disease progression, unacceptable toxicity, death or patient's decision for a maximum of 24 months.

Trial Locations (32)

Unknown

ACTIVE_NOT_RECRUITING

Centre de Radiothérapie du Pays d'Aix, Aix-en-Provence

RECRUITING

Centre Hospitalier du Pays d'Aix, Aix-en-Provence

RECRUITING

Institut du Cancer Avignon-Provence, Avignon

ACTIVE_NOT_RECRUITING

Centre d'Oncologie du Pays Basque, Bayonne

RECRUITING

CH de la côte Basque, Bayonne

NOT_YET_RECRUITING

Clinique Belharra, Bayonne

RECRUITING

Centre François Baclesse, Caen

RECRUITING

CHU de CAEN, Caen

RECRUITING

Centre Jean Perrin, Clermont-Ferrand

RECRUITING

CHI Créteil, Créteil

RECRUITING

Centre George François Leclerc, Dijon

RECRUITING

Centre Oscar Lambret, Lille

RECRUITING

CHU Dupuytren, Limoges

RECRUITING

Polyclinique de Limoges -Site Clinique Chénieux, Limoges

RECRUITING

Groupe Hospitalier Bretagne Sud, Lorient

NOT_YET_RECRUITING

Centre Léon Bérard, Lyon

RECRUITING

APHM - Hôpital Nord, Marseille

RECRUITING

Hopital européen Marseille, Marseille

ACTIVE_NOT_RECRUITING

Hopital privé Clairval, Marseille

RECRUITING

Institut Paoli-Calmettes, Marseille

RECRUITING

Institut régional du Cancer de Montpellier - ICM Val d'Aurelle, Montpellier

RECRUITING

Hopital privé du Confluent, Nantes

NOT_YET_RECRUITING

Centre Lacassagne, Nice

RECRUITING

Hôpital Tenon APHP, Paris

RECRUITING

Institut Curie, Paris

ACTIVE_NOT_RECRUITING

CARIO, Plérin

RECRUITING

Institut Godinot, Reims

RECRUITING

Centre Henri Becquerel, Rouen

RECRUITING

CH Saint Brieuc, Saint-Brieuc

NOT_YET_RECRUITING

Clinique Mutualiste de l'Estuaire, Saint-Nazaire

NOT_YET_RECRUITING

Centre d'oncologie Saint Yves, Vannes

RECRUITING

Hopital Nord Ouest - Villefranche sur Saône, Villefranche-sur-Saône

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

UNICANCER

OTHER