NCT05617677 - A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE) | Biotech Hunter

Enrollment

490

Participants

Timeline

Start Date

January 12, 2023

Primary Completion Date

December 17, 2025

Study Completion Date

December 17, 2027

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

Deucravacitinib

Specified dose on specified days

OTHER

Placebo

Specified dose on specified days

Trial Locations (222)

0

NOT_YET_RECRUITING

Local Institution - 0213, Vizianagaram

COMPLETED

Local Institution - 0119, Manorhamilton

33

ACTIVE_NOT_RECRUITING

Local Institution - 0103, Lima

1123

ACTIVE_NOT_RECRUITING

Local Institution - 0032, Buenos Aires

1406

ACTIVE_NOT_RECRUITING

Local Institution - 0020, CABA

1407

COMPLETED

Local Institution - 0217, Sofia

1784

ACTIVE_NOT_RECRUITING

Local Institution - 0162, Sofia

1878

ACTIVE_NOT_RECRUITING

Local Institution - 0078, Quilmes

2025

ACTIVE_NOT_RECRUITING

Local Institution - 0236, Chisinau

4000

ACTIVE_NOT_RECRUITING

Local Institution - 0123, San Miguel de Tucumán

ACTIVE_NOT_RECRUITING

Local Institution - 0163, Plovdiv

5004

ACTIVE_NOT_RECRUITING

Local Institution - 0138, Córdoba

5500

ACTIVE_NOT_RECRUITING

Local Institution - 0017, Mendoza

6760

WITHDRAWN

Local Institution - 0014, Mexico City

7405

WITHDRAWN

Local Institution - 0233, Cape Town

7600

WITHDRAWN

Local Institution - 0231, Stellenbosch

10016

ACTIVE_NOT_RECRUITING

Local Institution - 0085, New York

10467

COMPLETED

Local Institution - 0159, The Bronx

11030

ACTIVE_NOT_RECRUITING

Local Institution - 0180, Manhasset

14080

ACTIVE_NOT_RECRUITING

Local Institution - 0112, Mexico City

14642

ACTIVE_NOT_RECRUITING

Local Institution - 0098, Rochester

15046

ACTIVE_NOT_RECRUITING

Local Institution - 0104, Lima

15047

ACTIVE_NOT_RECRUITING

Local Institution - 0122, Lima

16499

ACTIVE_NOT_RECRUITING

Local Institution - 0101, Suwon

20122

COMPLETED

Local Institution - 0095, Milan

20132

COMPLETED

Local Institution - 0072, Milan

21100

ACTIVE_NOT_RECRUITING

Local Institution - 0015, Mexicali

23538

ACTIVE_NOT_RECRUITING

Local Institution - 0151, Lübeck

24016

COMPLETED

Local Institution - 0009, Roanoke

25123

ACTIVE_NOT_RECRUITING

Local Institution - 0069, Brescia

27100

WITHDRAWN

Local Institution - 0118, Pavia

28207

ACTIVE_NOT_RECRUITING

Local Institution - 0245, Charlotte

28211

ACTIVE_NOT_RECRUITING

Local Institution - 0155, Charlotte

29486

COMPLETED

Local Institution - 0246, Summerville

30044

NOT_YET_RECRUITING

Local Institution - 0228, Lawrenceville

WITHDRAWN

Local Institution - 0234, Lawrenceville

30046

ACTIVE_NOT_RECRUITING

Local Institution - 0147, Lawrenceville

30318

ACTIVE_NOT_RECRUITING

Local Institution - 0204, Atlanta

30463

ACTIVE_NOT_RECRUITING

Local Institution - 0210, Bucharest

31000

ACTIVE_NOT_RECRUITING

Local Institution - 0018, Chihuahua City

32610

ACTIVE_NOT_RECRUITING

Local Institution - 0010, Gainesville

32806

ACTIVE_NOT_RECRUITING

Local Institution - 0007, Orlando

33065

ACTIVE_NOT_RECRUITING

Local Institution - 0249, Coral Springs

33136

ACTIVE_NOT_RECRUITING

Local Institution - 0087, Miami

33189

WITHDRAWN

Nouvelle Clinical Research, Cutler Bay

33317

ACTIVE_NOT_RECRUITING

Local Institution - 0242, Plantation

33321

RECRUITING

Local Institution - 0002, Tamarac

33486

WITHDRAWN

Rheumatology Assoc. Of South Florida, Boca Raton

33603

WITHDRAWN

Genesis Clinical Research, LLC, Tampa

33614

COMPLETED

Local Institution - 0165, Tampa

34098

ACTIVE_NOT_RECRUITING

Local Institution - 0168, Istanbul

35015

WITHDRAWN

Local Institution - 0106, Junggu

35128

ACTIVE_NOT_RECRUITING

Local Institution - 0097, Padua

35205

ACTIVE_NOT_RECRUITING

Local Institution - 0012, Birmingham

37000

ACTIVE_NOT_RECRUITING

Local Institution - 0082, León

37032

COMPLETED

Local Institution - 0156, Tours

37134

ACTIVE_NOT_RECRUITING

Local Institution - 0161, Verona

38119

COMPLETED

Local Institution - 0003, Memphis

41380

ACTIVE_NOT_RECRUITING

Local Institution - 0189, Kocaeli

41944

WITHDRAWN

Local Institution - 0105, Junggu

45116

NOT_YET_RECRUITING

Local Institution - 0024, Zapopan

46202

COMPLETED

Local Institution - 0108, Indianapolis

47150

NOT_YET_RECRUITING

Lake Cumberland Rheumatology, New Albany

48202

COMPLETED

Local Institution - 0006, Detroit

50036

WITHDRAWN

Local Institution - 0055, Medellín

50937

ACTIVE_NOT_RECRUITING

Local Institution - 0061, Cologne

53132

COMPLETED

Local Institution - 0063, Franklin

55121

ACTIVE_NOT_RECRUITING

Local Institution - 0179, Eagan

56126

ACTIVE_NOT_RECRUITING

Local Institution - 0060, Pisa

60053

ACTIVE_NOT_RECRUITING

Local Institution - 0227, Morton Grove

60195

COMPLETED

Local Institution - 0077, Schaumburg

61469

COMPLETED

Local Institution - 0102, Gwangju

67091

COMPLETED

Local Institution - 0150, Strasbourg

70121

ACTIVE_NOT_RECRUITING

Local Institution - 0225, New Orleans

72076

ACTIVE_NOT_RECRUITING

Local Institution - 0109, Tübingen

72160

ACTIVE_NOT_RECRUITING

Local Institution - 0083, Puebla City

75013

ACTIVE_NOT_RECRUITING

Local Institution - 0064, Allen

75390

ACTIVE_NOT_RECRUITING

Local Institution - 0065, Dallas

76177

COMPLETED

Local Institution - 0088, Fort Worth

77090

ACTIVE_NOT_RECRUITING

Local Institution - 0250, Houston

77382

ACTIVE_NOT_RECRUITING

Local Institution - 0005, The Woodlands

79415

NOT_YET_RECRUITING

Local Institution - 0219, Lubbock

80131

ACTIVE_NOT_RECRUITING

Local Institution - 0154, Napoli

80230

COMPLETED

Local Institution - 0099, Denver

80336

ACTIVE_NOT_RECRUITING

Local Institution - 0176, Munich

82152

ACTIVE_NOT_RECRUITING

Local Institution - 0111, Planegg

85006

NOT_YET_RECRUITING

Local Institution - 0229, Phoenix

WITHDRAWN

Local Institution - 0230, Phoenix

85724

COMPLETED

Local Institution - 0193, Tucson

90095

ACTIVE_NOT_RECRUITING

Local Institution - 0124, Los Angeles

90623

ACTIVE_NOT_RECRUITING

Local Institution - 0090, La Palma

91054

ACTIVE_NOT_RECRUITING

Local Institution - 0120, Erlangen

91942

ACTIVE_NOT_RECRUITING

Local Institution - 0247, La Mesa

92128

ACTIVE_NOT_RECRUITING

Local Institution - 0253, San Diego

92335

NOT_YET_RECRUITING

Kaiser Permanente, Fontana

92543

WITHDRAWN

Private Practice - Dr. Chandrakant V. Mehta, Hemet

93108

COMPLETED

Local Institution - 0128, Santa Barbara

94270

ACTIVE_NOT_RECRUITING

Local Institution - 0173, Le Kremlin-Bicêtre

95817

ACTIVE_NOT_RECRUITING

Local Institution - 0248, Sacramento

98122

ACTIVE_NOT_RECRUITING

Local Institution - 0011, Seattle

98195

COMPLETED

Local Institution - 0139, Seattle

100730

ACTIVE_NOT_RECRUITING

Local Institution - 0070, Beijing

110001

ACTIVE_NOT_RECRUITING

Local Institution - 0039, Shenyang

110004

ACTIVE_NOT_RECRUITING

Local Institution - 0092, Shenyang

110221

ACTIVE_NOT_RECRUITING

Local Institution - 0100, Bogotá

110231

ACTIVE_NOT_RECRUITING

Local Institution - 0170, Bogotá

122001

ACTIVE_NOT_RECRUITING

Local Institution - 0208, Gurugram

200025

COMPLETED

Local Institution - 0079, Shanghai

200040

ACTIVE_NOT_RECRUITING

Local Institution - 0045, Shanghai

200127

ACTIVE_NOT_RECRUITING

Local Institution - 0049, Shanghai

200347

ACTIVE_NOT_RECRUITING

Local Institution - 0142, Craiova

213003

COMPLETED

Local Institution - 0129, Changzhou

233017

ACTIVE_NOT_RECRUITING

Local Institution - 0110, Bengbu

247065

ACTIVE_NOT_RECRUITING

Local Institution - 0094, Râmnicu Vâlcea

250001

COMPLETED

Local Institution - 0149, Jinan

ACTIVE_NOT_RECRUITING

Local Institution - 0057, Chía

300052

COMPLETED

Local Institution - 0053, Tianjin

300766

ACTIVE_NOT_RECRUITING

Local Institution - 0143, Timișoara

310003

ACTIVE_NOT_RECRUITING

Local Institution - 0132, Hangzhou

325000

COMPLETED

Local Institution - 0135, Wenzhou

330006

COMPLETED

Local Institution - 0071, Nanchang

ACTIVE_NOT_RECRUITING

Local Institution - 0117, Nanchang

ACTIVE_NOT_RECRUITING

Local Institution - 0220, Nanchang

332000

ACTIVE_NOT_RECRUITING

Local Institution - 0031, Jiujiang

337055

ACTIVE_NOT_RECRUITING

Local Institution - 0028, Pingxiang

361003

ACTIVE_NOT_RECRUITING

Local Institution - 0107, Xiamen

380015

ACTIVE_NOT_RECRUITING

Local Institution - 0200, Ahmedabad

395010

ACTIVE_NOT_RECRUITING

Local Institution - 0243, Surat

410008

ACTIVE_NOT_RECRUITING

Local Institution - 0044, Changsha

412007

ACTIVE_NOT_RECRUITING

Local Institution - 0021, Zhuzhou

430022

COMPLETED

Local Institution - 0137, Wuhan

450000

ACTIVE_NOT_RECRUITING

Local Institution - 0023, Zhengzhou

471003

ACTIVE_NOT_RECRUITING

Local Institution - 0133, Luoyang

500038

ACTIVE_NOT_RECRUITING

Local Institution - 0222, Hyderabad

500082

COMPLETED

Local Institution - 0205, Hyderabad

510000

ACTIVE_NOT_RECRUITING

Local Institution - 0029, Guangzhou

510080

COMPLETED

Local Institution - 0051, Guangzhou

510120

ACTIVE_NOT_RECRUITING

Local Institution - 0080, Guangzhou

518020

ACTIVE_NOT_RECRUITING

Local Institution - 0037, Shenzhen

560010

ACTIVE_NOT_RECRUITING

Local Institution - 0202, Bengaluru

610041

ACTIVE_NOT_RECRUITING

Local Institution - 0116, Chengdu

680003

ACTIVE_NOT_RECRUITING

Local Institution - 0086, Bucaramanga

700127

ACTIVE_NOT_RECRUITING

Local Institution - 0216, Iași

760035

WITHDRAWN

Local Institution - 0058, Santiago de Cali

ACTIVE_NOT_RECRUITING

Local Institution - 0093, Santiago de Cali

830001

ACTIVE_NOT_RECRUITING

Local Institution - 0043, Ürümqi

999077

COMPLETED

Local Institution - 0067, Tuenmen

15090000

COMPLETED

Local Institution - 0066, São José do Rio Preto

71635580

ACTIVE_NOT_RECRUITING

Local Institution - 0096, Lago Sul

90610000

ACTIVE_NOT_RECRUITING

Local Institution - 0181, Porto Alegre

06510

COMPLETED

Local Institution - 0054, New Haven

07901

ACTIVE_NOT_RECRUITING

Local Institution - 0177, Summit

C1121ABE

ACTIVE_NOT_RECRUITING

Local Institution - 0013, Buenos Aires

C1023AAB

ACTIVE_NOT_RECRUITING

Local Institution - 0240, Buenos Aires

C1221ADC

ACTIVE_NOT_RECRUITING

Local Institution - 0022, Buenos Aires

CP1280AEB

ACTIVE_NOT_RECRUITING

Local Institution - 0140, Buenos Aires

40150-150

ACTIVE_NOT_RECRUITING

Local Institution - 0224, Salvador

30150-221

ACTIVE_NOT_RECRUITING

Local Institution - 0042, Belo Horizonte

36010-570

ACTIVE_NOT_RECRUITING

Local Institution - 0041, Juiz de Fora

80730-150

COMPLETED

Local Institution - 0190, Curitiba

24020-096

WITHDRAWN

Local Institution - 0075, Niterói

13015-001

ACTIVE_NOT_RECRUITING

Local Institution - 0185, Campinas

14051-140

ACTIVE_NOT_RECRUITING

Local Institution - 0187, Ribeirão Preto

04038-002

ACTIVE_NOT_RECRUITING

Local Institution - 0191, São Paulo

20551-030

ACTIVE_NOT_RECRUITING

Local Institution - 0186, Rio de Janeiro

05403-000

ACTIVE_NOT_RECRUITING

Local Institution - 0125, São Paulo

05652-900

WITHDRAWN

Local Institution - 0048, São Paulo

T2N 4N1

ACTIVE_NOT_RECRUITING

Local Institution - 0126, Calgary

L8S 4K1

COMPLETED

Local Institution - 0160, Hamilton

N6A 4V2

ACTIVE_NOT_RECRUITING

Local Institution - 0114, London

M5T 2S8

ACTIVE_NOT_RECRUITING

Local Institution - 0115, Toronto

G5L 5T1

ACTIVE_NOT_RECRUITING

Local Institution - 0136, Rimouski

071030

COMPLETED

Local Institution - 0153, Baoding

014010

WITHDRAWN

Local Institution - 0059, Baotou

010050

ACTIVE_NOT_RECRUITING

Local Institution - 0089, Hohhot

030032

ACTIVE_NOT_RECRUITING

Local Institution - 0158, Taiyuan

050021

ACTIVE_NOT_RECRUITING

Local Institution - 0174, Medellín

080002

ACTIVE_NOT_RECRUITING

Local Institution - 0056, Barranquilla

44093 Cedex 1

ACTIVE_NOT_RECRUITING

Local Institution - 0068, Nantes

01307

ACTIVE_NOT_RECRUITING

Local Institution - 0146, Dresden

09117

ACTIVE_NOT_RECRUITING

Local Institution - 0195, Chemnitz

T12 E8YV

COMPLETED

Local Institution - 0130, Cork

D08 E9P6

COMPLETED

Local Institution - 0157, Dublin

D15 X40D

COMPLETED

Local Institution - 0172, Dublin

00161

ACTIVE_NOT_RECRUITING

Local Institution - 0084, Rome

LT-50161

ACTIVE_NOT_RECRUITING

Local Institution - 0167, Kaunas

01120

ACTIVE_NOT_RECRUITING

Local Institution - 0026, Mexico City

03720

NOT_YET_RECRUITING

Local Institution - 0027, Mexico City

06700

ACTIVE_NOT_RECRUITING

Local Institution - 0016, Mexico City

ACTIVE_NOT_RECRUITING

Local Institution - 0050, Mexico City

MD-2025

WITHDRAWN

Local Institution - 0237, Chisinau

MD-2051

ACTIVE_NOT_RECRUITING

Local Institution - 0238, Chisinau

05154

ACTIVE_NOT_RECRUITING

Local Institution - 0199, Arequipa

60-218

ACTIVE_NOT_RECRUITING

Local Institution - 0036, Poznan

60-446

WITHDRAWN

Local Institution - 0030, Poznan

85-168

ACTIVE_NOT_RECRUITING

Local Institution - 0040, Bydgoszcz

30-363

ACTIVE_NOT_RECRUITING

Local Institution - 0033, Krakow

50-381

WITHDRAWN

Local Institution - 0196, Wroclaw

05-830

ACTIVE_NOT_RECRUITING

Local Institution - 0034, Nadarzyn

02-118

ACTIVE_NOT_RECRUITING

Local Institution - 0164, Warsaw

02-637

ACTIVE_NOT_RECRUITING

Local Institution - 0166, Warsaw

005-200

WITHDRAWN

Local Institution - 0194, Wołomin

40-081

ACTIVE_NOT_RECRUITING

Local Institution - 0047, Katowice

15-707

ACTIVE_NOT_RECRUITING

Local Institution - 0035, Bialystok

20-362

RECRUITING

Velocity Clinical Research, Lublin, Lublin

60-702

ACTIVE_NOT_RECRUITING

Local Institution - 0212, Poznan

97-400

NOT_YET_RECRUITING

Local Institution - 0211, Bełchatów

2720-276

WITHDRAWN

Local Institution - 0073, Lisbon

00725

ACTIVE_NOT_RECRUITING

Local Institution - 0203, Caguas

00909

ACTIVE_NOT_RECRUITING

Local Institution - 0252, San Juan

00917

ACTIVE_NOT_RECRUITING

Local Institution - 0197, San Juan

011053

ACTIVE_NOT_RECRUITING

Local Institution - 0148, Bucharest

011172

ACTIVE_NOT_RECRUITING

Local Institution - 0076, Bucharest

014142

ACTIVE_NOT_RECRUITING

Local Institution - 0152, Bucharest

020125

ACTIVE_NOT_RECRUITING

Local Institution - 0141, Bucharest

041303

ACTIVE_NOT_RECRUITING

Local Institution - 0215, Bucharest

089 01

WITHDRAWN

Local Institution - 0207, Svidník

03601

WITHDRAWN

Local Institution - 0206, Martin

0001

WITHDRAWN

Local Institution - 0232, Pretoria

06591

ACTIVE_NOT_RECRUITING

Local Institution - 0144, Seoul

04763

ACTIVE_NOT_RECRUITING

Local Institution - 0169, Seoul

06560

ACTIVE_NOT_RECRUITING

Local Institution - 0184, Ankara