115
Participants
Start Date
February 1, 2023
Primary Completion Date
August 31, 2025
Study Completion Date
October 1, 2025
Pharmacokinetic (PK)- Controlled Feeding Diet
Pharmacokinetic- single-day isocaloric meals of beef, potatoes, chicken, whole wheat bread, corn, cheese, yogurt, and oats with blood and urine samples taken at Time Zero and every hour (blood) or two hours (urine) after eating, over 10 hours; and at 24 hr.
Dose Response (DR)- Controlled Feeding Diet
Dose Response-3 level, six days controlled feeding study with assignment to either beef/whole wheat bread, chicken/potato, salmon/corn, cheese/soybeans, or yogurt/oats within a standard diet at zero, medium, and high doses for 6 days.
Mass General Brigham Center for Clinical Investigation, Boston
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Harvard School of Public Health (HSPH)
OTHER