FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

PHASE1RecruitingINTERVENTIONAL
Enrollment

535

Participants

Timeline

Start Date

January 12, 2023

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Urinary Bladder NeoplasmsNeoplasm MetastasisUreteral Neoplasms
Interventions
DRUG

LOXO-435

Oral

DRUG

Pembrolizumab

IV

DRUG

enfortumab vedotin

IV

Trial Locations (84)

2065

RECRUITING

GenesisCare North Shore, St Leonards

2109

NOT_YET_RECRUITING

Macquarie University, Sydney

2310

RECRUITING

Calvary Mater Newcastle, Hunter Region, NSW

3015

RECRUITING

Erasmus MC, GE Rotterdam

5021

RECRUITING

Haukeland University Hospital, Bergen

10016

RECRUITING

New York University (NYU), New York

10021

NOT_YET_RECRUITING

Weill Cornell Medicine, New York

10029

RECRUITING

Icahn School of Medicine at Mount Sinai, New York

10032

NOT_YET_RECRUITING

Columbia University, New York

10065

RECRUITING

David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York

10467

NOT_YET_RECRUITING

Montefiore Medical Center, The Bronx

14642

RECRUITING

University of Rochester - Wilmot Cancer Institute, Rochester

15212

NOT_YET_RECRUITING

Allegheny General Hospital, Pittsburgh

15213

RECRUITING

University of Pittsburgh Medical Center, Pittsburgh

17601

RECRUITING

Penn Medicine Lancaster General Hospital - Ann B. Barshinger Cancer Institute, Lancaster

19104

RECRUITING

University of Pennsylvania, Philadelphia

19107

NOT_YET_RECRUITING

Thomas Jefferson University, Philadelphia

20132

RECRUITING

IRCCS Ospedale San Raffaele, Milan

22042

NOT_YET_RECRUITING

Inova Schar Cancer Institute, Falls Church

23538

NOT_YET_RECRUITING

Universitaetsklinikum Schleswig-Holstein - Campus Luebeck, Lübeck

27599

RECRUITING

University of North Carolina (UNC) - Chapel Hill, Chapel Hill

28033

RECRUITING

Fundacion MD Anderson International Espana, Madrid

28041

RECRUITING

Hospital Universitario 12 de Octubre, Madrid

28050

RECRUITING

South Texas Accelerated Research Therapeutics (START) Madrid - CIOCC, Madrid

29572

RECRUITING

Carolina Urologic Research Center, Myrtle Beach

30322

RECRUITING

Emory University Hospital, Atlanta

32804

RECRUITING

Advent Health, Orlando

33076

RECRUITING

Institut Bergonie, Bordeaux

37203

RECRUITING

Sarah Cannon and HCA Research Institute, Nashville

NOT_YET_RECRUITING

Tennessee Oncology, Nashville

37212

NOT_YET_RECRUITING

Vanderbilt University Medical Center, Nashville

39008

RECRUITING

Hospital Universitario Marques De Valdecilla, Santander

43210

RECRUITING

The Ohio State University (OSU), Columbus

45267

RECRUITING

University of Cincinnati Medical Center (UCMC), Cincinnati

46202

RECRUITING

Indiana University (IU) Melvin and Bren Simon Cancer Center, Indianapolis

48201

RECRUITING

Barbara Ann Karmanos Cancer Institute, Detroit

49100

RECRUITING

Rabin Medical Center, Beilinson Hospital, Petah Tikva

60637

RECRUITING

The University of Chicago Medical Center (UCMC), Chicago

63108

RECRUITING

Washington University in St. Louis, St Louis

69008

RECRUITING

Centre Leon Berard, Lyon

70121

NOT_YET_RECRUITING

Ochsner Clinic Foundation, New Orleans

70809

NOT_YET_RECRUITING

Mary Bird Perkins Cancer Center, Baton Rouge

72016

RECRUITING

Universitaetsklinikum Tuebingen, Tübingen

73104

RECRUITING

University of Oklahoma - Health Sciences Center, Oklahoma City

75244

RECRUITING

University of Texas Southwestern, Dallas

75251

RECRUITING

Texas Oncology, P.A, Dallas

77030

RECRUITING

MD Anderson Cancer Center, Houston

81675

RECRUITING

Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), München

84132

RECRUITING

University of Utah, Salt Lake City

85719

NOT_YET_RECRUITING

University of Arizona - Cancer Center, Tucson

90095

RECRUITING

University of California, Los Angeles (UCLA) - Division of Hematology-Oncology, Los Angeles

91010

RECRUITING

City of Hope, Duarte

92868

RECRUITING

University of California - Irvine, Orange

94305

NOT_YET_RECRUITING

Stanford Cancer Center, Stanford

94805

RECRUITING

Institut Gustave Roussy, Villejuif

95817

NOT_YET_RECRUITING

University of California (UC) Davis Comprehensive Cancer Center, Sacramento

100142

RECRUITING

Beijing Cancer hospital, Beijing

100730

RECRUITING

Beijing Hospital, Beijing

200000

RECRUITING

Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai

300060

RECRUITING

Tianjin Medical University Cancer Institute & Hospital, Tianjin

310002

RECRUITING

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou

310003

RECRUITING

Zhejiang Provincial People's Hospital, Zhejiang

510060

RECRUITING

Sun Yat-Sen University- Cancer Center, Guangdong

710061

RECRUITING

First Affiliated Hospital of Medical College of Xian jiaotong University, Xi'an

5265601

RECRUITING

Sheba Medical Center, Tel Litwinsky

21231-2410

RECRUITING

Johns Hopkins Kimmel Cancer Center, Baltimore

02114

RECRUITING

Massachusetts General Hospital, Boston

05401

NOT_YET_RECRUITING

University of Vermont Medical Center, Burlington

NSW 2010

RECRUITING

St Vincent's Hospital, Darlinghurst

M5G 2M9

RECRUITING

Princess Margaret Hospital, Toronto

V5Z 1J3

RECRUITING

British Columbia Cancer Agency, Vancouver

00168

RECRUITING

UOC Fase I - Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore, Roma

277-8577

RECRUITING

National Cancer Center Hospital East, Chiba

464-8681

RECRUITING

Aichi Cancer Center Hospital, Nagoya

104-0045

RECRUITING

National Cancer Center Hospital, Tokyo

135-8550

RECRUITING

Cancer Institute Hospital of JFCR, Tokyo

0450

RECRUITING

Oslo University Hospital, Oslo

03080

RECRUITING

Seoul National University Hospital, Seoul

03722

RECRUITING

Severance Hospital, Yonsei University Health System, Seoul

05505

RECRUITING

Asan Medical Center, Seoul

06351

RECRUITING

Samsung Medical Center, Seoul

08908

RECRUITING

Institut Catala d'Oncologia - L'Hospitalet, Barcelona

M20 4BX

RECRUITING

The Christie NHS Foundation Trust, Manchester

S10 2SB

RECRUITING

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield

All Listed Sponsors
lead

Eli Lilly and Company

INDUSTRY