Are Uterine Fibroids Pro-thrombotic?

Active, not recruitingOBSERVATIONAL
Enrollment

105

Participants

Timeline

Start Date

October 17, 2022

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Leiomyoma, UterineThrombosis
Interventions
OTHER

Comparison of blood samples between the two groups

In this study we will perform global haemostatic assays such as activated partial thromboplastic time (APTT), and prothrombin time (PT). However, these tests provide information about the haemostatic process until the point of initial fibrin formation and ignore the procedure of thrombin generation\[18\]. In this study we will perform Thrombin Generation studies, Plasma clot Lysis, and RNA sequencing in addition to standard laboratory tests (APTT, PT, FVIII:C, fibrinogen (using Clauss methods), platelet count, liver and renal function tests.

Trial Locations (1)

SE5 9RS

King's College Hospital, London

All Listed Sponsors
collaborator

Hemab ApS

INDUSTRY

lead

King's College Hospital NHS Trust

OTHER