Preventing Sensory and Motor Dysfunctions in Children Receiving Neurotoxic Chemotherapy

NARecruitingINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

December 1, 2022

Primary Completion Date

March 31, 2025

Study Completion Date

March 31, 2026

Conditions
Chemotherapy-induced Peripheral NeuropathyPediatric Cancer
Interventions
BEHAVIORAL

Playful sensorimotor training

"For the max. duration of the first in-hospital phase (3weeks), all children will receive supervised training. When children go home they will be supplied with a manual, specific exercises and the necessary training devices. Regular supervision will allow to ensure that the training is performed at maximum benefit. Each session will last for about 20 to 30 minutes in total, including a child-specific warm-up and cool-down. The children will be asked to maintain balance in a previously acquired short-foot-position, knees slightly flexed (30°), without shoes. Training will consist of 5 playful balance exercises chosen from a standardized pool of exercises according to the child's age, with increasing difficulty in order to allow for individual, optimal progression. Each of the 5 exercises will contain of 5 repetitions for 10sec. allowing for a 20sec. rest in between each set and a 1min rest between each exercise in order to avoid neural fatigue."

Trial Locations (2)

4056

NOT_YET_RECRUITING

Kantonspital Aarau, Basel

RECRUITING

UKBB Kinderspital, Basel

All Listed Sponsors
collaborator

Insel Gruppe AG, University Hospital Bern

OTHER

collaborator

Kantonsspital Aarau

OTHER

collaborator

Ostschweizer Kinderspital

OTHER

collaborator

University Hospital Heidelberg

OTHER

collaborator

University Hospital Freiburg

OTHER

collaborator

Krebsforschung Schweiz, Bern, Switzerland

OTHER

collaborator

Clinical Trial Unit, University Hospital Basel, Switzerland

OTHER

collaborator

Charite University, Berlin, Germany

OTHER

collaborator

National Center for Tumor Diseases, Heidelberg

OTHER

lead

University of Basel

OTHER