Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS

PHASE4CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

November 10, 2022

Primary Completion Date

March 5, 2023

Study Completion Date

March 5, 2023

Conditions
Functional Endoscopic Sinus SurgeryPremedicationAnalgesia
Interventions
DRUG

Intranasal dexmedetomidine

45 -60 min before the operation, patients will receive dose of dexmedetomidine 1microgram/kg diluted in 10ml 0.9% saline administered to each naris as drops + infusion saline

DRUG

Intravenous dexmedetomidine

patients will receive loading dose of dexmedetomidine 1 µg/kg diluted in 10ml 0.9% saline infused over 45- 60 min before induction of anesthesia, followed by continuous infusion of (0.4 µ g/kg/h) + intranasal saline.

Trial Locations (1)

34711

Facualty of Medicine(Damietta), Al Azhar University, Damietta

All Listed Sponsors
lead

Al-Azhar University

OTHER