NCT05600842View on ClinicalTrials.gov

De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

RecruitingOBSERVATIONAL
Enrollment

111

Participants

Timeline

Start Date

November 3, 2022

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions
RADIATION

Intensity-Modulated Radiation Therapy (IMRT)

IMRT will be given in 30 daily fractions at 2 Gy per fraction (60 Gy total) beginning Day 1; Six fractions will be delivered per week. High risk patients will receive induction chemotherapy with 2 cycles of carboplatin and paclitaxel.

Trial Locations (1)

92868

RECRUITING

Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange

All Listed Sponsors
lead

University of California, Irvine

OTHER