Investigation of Autonomic Dysfunction in Patients With Familial Mediterranean Fever

UnknownOBSERVATIONAL
Enrollment

60

Participants

Timeline

Start Date

March 15, 2022

Primary Completion Date

October 31, 2022

Study Completion Date

October 31, 2022

Conditions
Familial Mediterranean FeverAutonomic Dysfunction
Interventions
DIAGNOSTIC_TEST

Composite Autonomic Symptom Score-31

Standardized questionnaire to determine the level of autonomic dysfunction

DIAGNOSTIC_TEST

r-r interval variability with normal breathing

electrophysiological test to detect parasympathetic dysfunction

DIAGNOSTIC_TEST

r-r interval variability with deep breathing

electrophysiological test to detect parasympathetic dysfunction

DIAGNOSTIC_TEST

Valsalva ratio

electrophysiological test to detect parasympathetic dysfunction

DIAGNOSTIC_TEST

30:15 ratio

electrophysiological test to detect parasympathetic dysfunction

DIAGNOSTIC_TEST

sympathetic skin response

electrophysiological test to detect sympathetic dysfunction

DIAGNOSTIC_TEST

blood pressure response to standing

clinical test to detect sympathetic dysfunction

DIAGNOSTIC_TEST

blood pressure response to sustained handgrip test

clinical test to detect sympathetic dysfunction

OTHER

Hospital anxiety and depression scale

Standardized questionnaire to investigate the depression and anxiety

DIAGNOSTIC_TEST

Fibromyalgia rapid screening tool

Standardized questionnaire to determine the presence of fibromyalgia

OTHER

Familial Mediterranean Fever Quality of life scale

Standardized questionnaire to investigate the quality of life in Familial Mediterranean Fever patients

OTHER

Jenkins Sleep Evaluation Scale

Standardized questionnaire to investigate the sleep quality and disturbance

OTHER

The Fatigue Severity Scale

Standardized questionnaire to investigate the fatigue severity

Trial Locations (1)

Unknown

RECRUITING

Marmara University School of Medicine, Pendik Education and Research Hospital, Department of Physical Medicine and Rehabilitation, Istanbul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Marmara University

OTHER

NCT05596643 - Investigation of Autonomic Dysfunction in Patients With Familial Mediterranean Fever | Biotech Hunter | Biotech Hunter