Whether Opioids Are Factor That Induced POD?

NACompletedINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

June 25, 2016

Primary Completion Date

July 15, 2020

Study Completion Date

December 31, 2020

Conditions
Postoperative Delirium
Interventions
DRUG

Sufentanil Citrate

Intraoperative loading dose of sufentanil 0.6μg/kg, each additional hour 10μg, within one hour of the end of surgery to stop additional.Postoperative analgesia pump formula: sufentanil 150ug + 0.75% ropivacaine 60ml with 0.9% saline diluted to 220ml, 3ml

DRUG

Ropivacaine 0.75% Injectable Solution

Intraoperative epidural analgesia was performed with 0.5% ropivacaine 5-20 ml,Postoperative analgesia pump formula:0.75% ropivacaine 60ml with 0.9% saline diluted to 220ml, 3ml/h, Blos 3ml, locking time 15min, the maximum dose of 36ml in 4 hours Saline is used to dilute other drugs

PROCEDURE

Epidural catheter

Intraoperative and postoperative analgesia

Trial Locations (1)

310022

Zhejiang Cancer Hospital, Hangzhou

All Listed Sponsors
lead

Zhejiang Cancer Hospital

OTHER

NCT05596071 - Whether Opioids Are Factor That Induced POD? | Biotech Hunter | Biotech Hunter