Causal Role of Frontostriatal Circuitry in Goal-directed Behavior

NACompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

January 10, 2023

Primary Completion Date

July 31, 2023

Study Completion Date

July 31, 2023

Conditions
Executive Function
Interventions
DEVICE

Delta-beta TMS

TMS will be delivered in a delta-beta pattern in which triplets of pulses delivered at 20 Hz (50 milliseconds between each pulse) are sent every 3 Hz (333 milliseconds between the start of each triplet).

DEVICE

Theta-gamma TMS

TMS will be delivered in a theta-gamma pattern in which triplets of pulses delivered at 50 Hz (20 milliseconds between each pulse) are sent every 5 Hz (200 milliseconds between the start of each triplet).

DEVICE

Arrhythmic TMS

TMS will be delivered in an arrhythmic pattern in which pulses are delivered with a random inter-pulse interval. The number of pulses and duration is matched to that of the Delta-beta TMS and Theta-gamma TMS.

Trial Locations (1)

27599

University of North Carolina at Chapel Hill, Chapel Hill

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of North Carolina, Chapel Hill

OTHER