NCT05590923View on ClinicalTrials.gov

Steroid-sparing Therapy (Olanzapine) Versus Dexamethasone-based Therapy for Chemotherapy-induced Nausea and Vomiting

PHASE4RecruitingINTERVENTIONAL
Enrollment

104

Participants

Timeline

Start Date

December 7, 2022

Primary Completion Date

November 1, 2028

Study Completion Date

November 1, 2029

Conditions
Chemotherapy-induced Nausea and Vomiting
Interventions
DRUG

OLA group: Olanzapine

"OLA group: olanzapine 10 mg oral each night on days 1-4 after HEC (or days 1-3 after MEC).~DEX group: dexamethasone (Decadron) 8 mg oral daily on days 2-4 after HEC (or days 2-3 after MEC)."

DRUG

DEX group: Dexamethasone

"DEX group: dexamethasone (Decadron) 8 mg oral daily on days 2-4 after HEC (or days 2-3 after MEC)..~OLA group: olanzapine 10 mg oral each night on days 1-4 after HEC (or days 1-3 after MEC)."

Trial Locations (1)

18840

RECRUITING

Robert Packer Hospital, Sayre

All Listed Sponsors
lead

The Guthrie Clinic

OTHER