NCT05589181View on ClinicalTrials.gov

High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)

PHASE3RecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

April 6, 2023

Primary Completion Date

September 1, 2026

Study Completion Date

December 31, 2026

Conditions
Opioid Use Disorder
Interventions
DRUG

High Dose Buprenorphine

32mg of BUP split as 16mg at 0 minutes and 16mg at 30-60 min as an induction dose

DRUG

Standard Buprenorphine Dose

12mg of buprenorphine (BUP) split as 8mg at 0 minutes and 4mg at time 30-60 min as an induction dose

Trial Locations (1)

07103

RECRUITING

Rutgers University Hospital, Newark

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Rutgers, The State University of New Jersey

OTHER