A Randomized Trial Comparing Optimized rhTPO Treatment With Eltrombopag Treatment in Pre-treated ITP Pts

PHASE4CompletedINTERVENTIONAL
Enrollment

157

Participants

Timeline

Start Date

November 22, 2022

Primary Completion Date

February 28, 2024

Study Completion Date

July 16, 2024

Conditions
Previously Treated Primary Immune Thrombocytopenia
Interventions
DRUG

rhTPO

initial therapy: rhTPO s.c, 300 or 600U/kg daily based on baseline platelet count; maintenance therapy: rhTPO s.c, 300 \~ 600U/kg every other day depends on platelet count.

DRUG

Eltrombopag

initial therapy: Eltrombopag oral, 25 or 50mg daily based on baseline platelet count; maintenance therapy: Eltrombopag oral, 25 \~ 75mg daily or every other day depends on platelet count.

Trial Locations (17)

116000

The Second Hospital of Dalian Medical University, Dalian

150000

The Second Affiliated Hospital of Harbin Medical University, Harbin

300020

Chinese Academy of Medical Science and Blood Disease Hospital,CAMS & PUMC, Tianjin

300211

The Second Hospital of Tianjin Medical University, Tianjin

315400

Yuyao People's Hospital of Zhejiang Province, Yuyao

450008

Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou

530007

The Second Affiliated Hospital of Guangxi Medical University, Nanning

650101

The Second Affiliated Hospital of Kunming Medical University, Kunming

710032

Xi'an Central Hospital, Xi'an

Xijing Hospital of the Fourth Military Medical University, Xi'an

710068

Shaanxi Provincial People's Hospital, Xi'an

830001

People's Hospital of Xinjiang Uygur Autonomous Region, Ürümqi

830011

The first affiliated Hospital of Xinjiang Medical University, Ürümqi

844000

Kashgar District 1st People's Hospital, Kashgar

050000

the Second Hospital of HeBei Medical University, Shijiazhuang

063000

North China University of Science and Technology Affiliated Hospital, Tangshan

010107

The Affiliated Hospital of Inner Mongolia Medical University, Hohhot

All Listed Sponsors
collaborator

The Second Hospital of Hebei Medical University

OTHER

collaborator

Xijing Hospital

OTHER

collaborator

The Affiliated Hospital of Inner Mongolia Medical University

OTHER

collaborator

The Second Affiliated Hospital of Kunming Medical University

OTHER

collaborator

Second Affiliated Hospital of Guangzhou Medical University

OTHER

collaborator

Shaanxi Provincial People's Hospital

OTHER

collaborator

Henan Cancer Hospital

OTHER_GOV

collaborator

North China University of Science and Technology

OTHER

collaborator

The Second Affiliated Hospital of Dalian Medical University

OTHER

collaborator

Second Hospital of Shanxi Medical University

OTHER

collaborator

The Second Affiliated Hospital of Harbin Medical University

OTHER

collaborator

Shenyang Sunshine Pharmaceutical Co., LTD.

INDUSTRY

collaborator

First Affiliated Hospital of Xinjiang Medical University

OTHER

collaborator

People's Hospital of Xinjiang Uygur Autonomous Region

OTHER

collaborator

Kashgar 1st People's Hospital

OTHER

collaborator

Xi'an Central Hospital

OTHER

collaborator

Beijing Public Health Foundation

UNKNOWN

collaborator

Yuyao People's Hospital

OTHER

lead

Institute of Hematology & Blood Diseases Hospital, China

OTHER